Hashimoto’s symptoms

Hashimoto's disease, an autoimmune disorder, primarily affects the thyroid, leading to symptoms like fatigue, weight gain, and cold intolerance. It often causes an underactive thyroid (hypothyroidism), resulting in slowed metabolism. Additional symptoms include dry skin, hair loss, and muscle weakness.

Persistent tiredness and lethargy, despite adequate rest.

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Fatigue

Unexplained weight gain or difficulty in losing weight, despite no change in diet or exercise routine.

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Weight gain

Dry, pale skin and brittle, thinning hair.

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Dry skin and hair

Difficulty in passing stools and infrequent bowel movements.

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Constipation

Increased sensitivity to cold, with a low tolerance for cold temperatures.

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Cold sensitivity

Weakness and aching in the muscles, especially in the arms and legs.

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Muscle weakness

Joint stiffness and pain, often affecting the hands and feet.

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Joint pain

Persistent feelings of sadness, hopelessness, and lack of interest in activities.

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Depression

Difficulty in concentrating, memory lapses, and cognitive impairment.

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Memory problems

Irregular or heavy menstrual periods in women.

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Menstrual irregularities

These symptoms can vary in severity and may develop gradually over time. It's important to consult a healthcare professional for proper diagnosis and management of Hashimoto's thyroiditis.

Grave’s symptoms

Swelling of the thyroid gland

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Enlarged thyroid gland (goiter), visible as a swelling at the base of the neck.

Anxiety and Irritability

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Individuals with Graves' disease may experience heightened nervousness, irritability, and anxiety.

Despite maintaining a normal or increased appetite, people with Graves' disease often experience unexplained weight loss.

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Unexplained Weight Loss

Tremors and Hyperactivity

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Tremors in the hands and fingers, as well as increased hyperactivity, can be indicative of Graves' disease.

Individuals may become more sensitive to heat, leading to excessive sweating and discomfort in warm environments.

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Heat Sensitivity

Fatigue and Muscle Weakness

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Persistent fatigue, muscle weakness, and a general feeling of weakness can be prevalent symptoms.

Irregular Heartbeat

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An increased heart rate or palpitations can occur in individuals with Graves' disease, along with potential heart rhythm disturbances.

Bulging Eyes (Exophthalmos)

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Some individuals may develop bulging or protruding eyes, known as exophthalmos, due to inflammation and swelling of the eye muscles and tissues.

Irregular Menstrual Cycles

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Women with Graves' disease may experience irregular menstrual cycles or a complete lack of menstruation.

Thinning of Skin and Hair

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Skin thinning and brittle hair due to weakened hair follicles can also occur as a result of Graves' disease.

Enlarged Thyroid (Goiter)

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A visible swelling at the base of the neck, known as a goiter, may develop due to an enlarged thyroid gland.

It's important to note that not all individuals with Graves' disease will experience the same combination or severity of symptoms. If someone suspects they may have Graves' disease, it's crucial to seek medical evaluation and care for proper diagnosis and management.

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Autoimmune Thyroid Disease

Hashimoto's Thyroiditis

Hashimoto's thyroiditis is an autoimmune disorder that primarily affects the thyroid gland. In this condition, the immune system mistakenly attacks the thyroid, leading to inflammation and eventual damage to the gland. Hashimoto's thyroiditis is the most common cause of hypothyroidism (underactive thyroid) in the United States.

Key features of Hashimoto's thyroiditis include:

Autoimmune Attack

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The immune system produces antibodies that target the thyroid tissue, specifically thyroglobulin and thyroid peroxidase, which are crucial components in the production of thyroid hormones. This autoimmune attack leads to chronic inflammation of the thyroid.

Gradual Thyroid Dysfunction

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Over time, the continuous inflammation can impair the thyroid's ability to produce an adequate amount of thyroid hormones (T3 and T4), resulting in hypothyroidism. This gradual decline in thyroid function may cause symptoms such as fatigue, weight gain, sensitivity to cold, and dry skin.

Goiter Formation

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The thyroid gland may become enlarged, causing a goiter. The goiter is a result of the thyroid attempting to compensate for the decreased hormone production by increasing its size. Not everyone with Hashimoto's thyroiditis develops a goiter.

Antibody Presence

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Blood tests can reveal the presence of specific antibodies (anti-thyroid peroxidase antibodies and anti-thyroglobulin antibodies) that indicate an autoimmune attack on the thyroid.

Symptoms of Hypothyroidism

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As the disease progresses, individuals may experience symptoms associated with an underactive thyroid, including fatigue, weight gain, constipation, hair loss, and muscle weakness.

Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the front of the neck, just below the Adam's apple. It plays a crucial role in regulating various metabolic processes in the body.

The main functions of the thyroid gland include:

Hormone Production

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The thyroid gland produces two main hormones, thyroxine (T4) and triiodothyronine (T3). These hormones are essential for the regulation of metabolism, which influences the rate at which the body converts food into energy.

Metabolic Regulation

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Thyroid hormones affect the metabolism of almost every cell in the body. They control the basal metabolic rate (BMR), which is the amount of energy the body needs at rest to maintain essential functions such as breathing and circulation.

Development and Growth

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Thyroid hormones are critical for the normal development and growth of tissues, especially in children. They play a role in the development of the brain and the maturation of the central nervous system.

Temperature Regulation

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Thyroid hormones help regulate body temperature by influencing the rate at which the body generates heat.

Regulation of Other Hormones

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The thyroid gland also interacts with other endocrine glands, such as the pituitary gland, to maintain a balance of hormones in the body.

Thyroid function is controlled by the pituitary gland, which releases thyroid-stimulating hormone (TSH) to stimulate the thyroid to produce and release its hormones. Imbalances in thyroid function can lead to various health issues, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid).

Grave's Disease

Graves' disease is an autoimmune disorder that primarily affects the thyroid gland. In this condition, the immune system mistakenly produces antibodies that stimulate the thyroid to produce excessive amounts of thyroid hormones. This leads to hyperthyroidism, a state where the thyroid is overactive.

Key features of Graves' disease include:

Thyroid Hormone Overproduction

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The antibodies produced in Graves' disease mimic the action of thyroid-stimulating hormone (TSH), leading to an uncontrolled release of thyroid hormones (T3 and T4). This excess of thyroid hormones accelerates the body's metabolism.

Enlarged Thyroid (Goiter)

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The thyroid gland may become enlarged, causing a noticeable swelling in the neck known as a goiter. The increased activity of the gland is often associated with an increased blood flow, contributing to the enlargement.

Eye and Skin Changes

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Graves' disease can also affect the eyes, leading to a condition known as Graves' ophthalmopathy or thyroid eye disease. This may cause bulging eyes, redness, irritation, and in severe cases, vision problems. Skin changes, such as red or swollen skin on the shins (pretibial myxedema), can also occur.

Nervous System Symptoms

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Patients with Graves' disease may experience symptoms related to an overactive nervous system, such as anxiety, irritability, tremors, and difficulty concentrating.

Weight Loss despite Increased Appetite

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Due to the increased metabolic rate associated with hyperthyroidism, individuals with Graves' disease may experience weight loss despite having an increased appetite.

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